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Butrans Trial Offer Card

For your FIRST prescription

Commercially insured, eligible patients can receive up to $100 in co-pay assistance on the first Butrans prescription.

  • Patients are responsible to pay for any prescription amount that exceeds $100

  • Only patients new to the Butrans Savings Program are eligible for the Trial Offer

  • Patients whose prescriptions for Butrans are covered under Medicare, Medicaid, or other government programs are not eligible

  • Patients who pay cash for a Butrans prescription are not eligible for the Trial Offer Card (but are eligible for the Savings Card)

Please see Eligibility Requirements and Terms and Conditions below.

For questions, please call the Butrans Patient Savings Program at 1-866-747-9674.

If you are eligible for both the Trial Offer Card and the Savings Card, you only need to print/download one card.


You can activate your card after it’s printed or downloaded.

Eligibility Requirements

These cards cannot be used if patient’s prescriptions are covered by: (i) any federal or state healthcare program, including a state medical or pharmaceutical assistance program (Medicare, Medicaid, Medigap, VA, DOD, TRICARE, etc.); (ii) Medicare Prescription Drug Program (Part D Program); or (iii) insurance in states that have an “all payer” anti-kickback law or insurance that is paying the entire cost of the prescription. Cash-paying patients are not eligible for the Butrans Trial Offer. Card use must comply with all Terms and Conditions. Limit one Savings Card per patient. Void where prohibited by law. Patients in Vermont are not eligible. Patients must meet eligibility requirements. Other restrictions may apply.

Terms and Conditions

Patients must meet eligibility requirements. Patient agrees to report their use of these cards to any third party that reimburses them or pays for any part of the prescription price. Patient additionally agrees to not submit any portion of the product dispensed pursuant to these cards to a federal or state healthcare program for purposes of counting it toward their out-of-pocket expenses (such as TrOOP under Medicare Part D or Medicaid). These cards are not valid with any other program, discount, or incentive involving the covered medication. This offer is not contingent upon any past, present, or future purchases of the covered drug or any other product, and this offer may be rescinded, revoked, or amended without notice. No reproductions. These cards are not insurance. These cards are void where prohibited or where restricted beyond the terms herein.


See additional resources, such as the Patch Application & Rotation Tutorial.

WARNING: ADDICTION, ABUSE, AND MISUSE; LIFE-THREATENING BREATHING PROBLEMS; ACCIDENTAL EXPOSURE; WITHDRAWAL SYNDROME IN NEWBORNS; and RISKS FROM USE WITH BENZODIAZEPINES OR OTHER CNS DEPRESSANTS

Addiction, Abuse, and Misuse

Butrans is a long-acting (extended-release) opioid pain medicine that can put you and other users at risk for overdose and death. Even if you use your dose correctly as prescribed, you are at risk for opioid addiction, abuse, and misuse that can lead to death.

Life-Threatening Breathing Problems

When you first start using Butrans, or when your dose is increased, serious or life-threatening breathing problems that can lead to death may occur, and may occur even at recommended doses during the normal course of therapy. Do not chew, swallow, snort, or inject buprenorphine from the patch because this can lead to overdose and death.

Accidental Exposure

Accidental exposure, especially in children, may result in breathing problems, overdose, or death.

Withdrawal Syndrome in Newborns

Prolonged use of Butrans when you are pregnant can cause withdrawal symptoms in your newborn baby that may be life-threatening if not recognized and treated.

Use with Benzodiazepines or Other CNS Depressants

Use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, can result in severe drowsiness, breathing problems, coma and death.

What is Butrans?
  • Butrans is a strong prescription pain medicine that contains an opioid (narcotic). It is used to manage pain severe enough to require daily, around-the-clock, long-term treatment with an opioid, when other pain treatments, such as non-opioid pain medicines (e.g., acetaminophen, ibuprofen, or celecoxib) or immediate-release opioid medicines, do not treat your pain well enough, you experience side effects when taking them, or they are deemed otherwise inadequate.

  • Butrans is only used to treat pain that continues around-the-clock (pain that is constant).

IMPORTANT SAFETY INFORMATION

Butrans is a long-acting (extended-release) opioid pain medicine that can put you at risk for overdose and death. Even if you use your dose correctly as prescribed, you are at risk for opioid addiction, abuse and misuse that can lead to death.

Do not use Butrans if you:

  • Have severe asthma, trouble breathing, or other lung problems

  • Have a bowel blockage or narrowing of the stomach or intestines

  • Are allergic to buprenorphine

Before applying Butrans, tell your healthcare provider if you have a history of head injury or seizures; problems breathing or urinating; liver, kidney, thyroid, pancreas, or gallbladder problems; heart rhythm abnormalities (Long QT Syndrome); abuse of street or prescription drugs; alcohol addiction; or mental health problems.

WARNINGS
  • Use of Butrans, even when used as recommended, can result in addiction, abuse and misuse, which could lead to overdose and death.

  • Get emergency help right away if you take too much Butrans (overdose).

  • The risk of serious or life-threatening breathing problems that could lead to death can occur even at recommended doses. The risk is greatest when you first start using Butrans or when your dose is increased. Patients who have lung disease or are elderly, frail, or in poor general health, are at increased risk, especially if Butrans is given with other drugs that cause breathing problems. Seek medical attention immediately if you have trouble breathing.

  • Taking Butrans with other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants (including street drugs) can cause severe drowsiness, decreased awareness, breathing problems, coma, and death. Do not use these together unless you are directed to do so by your healthcare provider.

  • Never give anyone else your Butrans. They could die from using it. Store Butrans away from children and in a safe place to help prevent abuse or theft. Selling or giving away Butrans is against the law.

  • Accidental exposure, especially in a child, may result in breathing problems, overdose, or death. Be sure to store Butrans safely and to dispose of unused patches when Butrans is no longer needed; use the Patch-Disposal Unit or fold the patch in half and flush it down the toilet (see the detailed Instructions for Use provided with the Butrans patch).

  • Tell your healthcare provider if you are pregnant or planning to become pregnant. Prolonged use of Butrans while you are pregnant can cause withdrawal symptoms in your newborn baby that could be life-threatening if not recognized and treated.

  • Tell your healthcare provider if you are breastfeeding. Breastfeeding is not recommended during treatment with Butrans. It may harm your baby.

  • Tell your healthcare provider about any prescription or over-the-counter medicines, vitamins, or herbal supplements you are taking. Using Butrans with certain other medicines can cause serious side effects that could lead to death.

  • When using Butrans, do not drink alcohol or use prescription or over-the-counter medicines containing alcohol. Using products containing alcohol during treatment with Butrans may cause you to overdose and die.

  • Butrans could cause adrenal insufficiency, a potentially life-threatening condition which may cause symptoms of nausea, vomiting, anorexia, fatigue, weakness, dizziness and low blood pressure. Seek medical attention if you experience these symptoms.

  • Butrans may cause symptoms of low blood pressure such as dizziness, lightheadedness, or fainting. If you experience these symptoms, you should sit or lie down and be careful when you get up from a sitting or lying position.

  • Butrans may complicate head injuries. Butrans should not be used by those with disturbances in consciousness or coma.

  • Do not stop using Butrans without talking to your healthcare provider.

  • Tell your healthcare provider if you develop a fever. While using Butrans, do NOT expose Butrans or the skin near where Butrans is applied to hot water or prolonged direct sunlight; avoid sunbathing, taking hot baths, hot tubs, saunas, heating pads, electric blankets, heated waterbeds, and heat or tanning lamps. These activities can increase the amount of medicine your Butrans delivers and cause an overdose that can lead to death.

  • Get emergency medical help if you have trouble breathing, shortness of breath, fast heartbeat, chest pain, swelling of your face, tongue or throat, extreme drowsiness, light-headedness when changing positions feeling faint, agitation, high body temperature, trouble walking, stiff muscles, or mental changes such as confusion.

  • Butrans may increase the frequency of seizures in patients who experience seizures and may increase the risk of seizures in other settings associated with seizures. Tell your healthcare provider if you have a history of seizures.

  • When using Butrans, do not drive or operate heavy machinery until you know how Butrans affects you. Butrans can make you sleepy, dizzy, or lightheaded, and may reduce your mental and physical ability to perform these activities safely.

Side Effects
  • The most common side effects reported by patients treated with Butrans in the clinical trials were nausea, headache, application site itch, dizziness, constipation, sleepiness, vomiting, application site redness, dry mouth, and application site rash. Call your healthcare provider if you have any of these symptoms and they are severe.

  • These are not all the possible side effects of Butrans. Call your doctor for medical advice about side effects.

Please read the Brief Summary and Full Prescribing Information, including Boxed Warning, Medication Guide, and Instructions for Use.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Indications and Usage
What is Butrans?
  • Butrans is a strong prescription pain medicine that contains an opioid (narcotic). It is used to manage pain severe enough to require daily, around-the-clock, long-term treatment with an opioid, when other pain treatments, such as non-opioid pain medicines (e.g., acetaminophen, ibuprofen, or celecoxib) or immediate-release opioid medicines, do not treat your pain well enough, you experience side effects when taking them, or they are deemed otherwise inadequate.

  • Butrans is only used to treat pain that continues around-the-clock (pain that is constant).

Important Safety Information

WARNING: ADDICTION, ABUSE, AND MISUSE; LIFE-THREATENING BREATHING PROBLEMS; ACCIDENTAL EXPOSURE; WITHDRAWAL SYNDROME IN NEWBORNS; and RISKS FROM USE WITH BENZODIAZEPINES OR OTHER CNS DEPRESSANTS

Addiction, Abuse, and Misuse

Butrans is a long-acting (extended-release) opioid pain medicine that can put you and other users at risk for overdose and death. Even if you use your dose correctly as prescribed, you are at risk for opioid addiction, abuse, and misuse that can lead to death.

Life-Threatening Breathing Problems

When you first start using Butrans, or when your dose is increased, serious or life-threatening breathing problems that can lead to death may occur, and may occur even at recommended doses during the normal course of therapy. Do not chew, swallow, snort, or inject buprenorphine from the patch because this can lead to overdose and death.

Accidental Exposure

Accidental exposure, especially in children, may result in breathing problems, overdose, or death.

Withdrawal Syndrome in Newborns

Prolonged use of Butrans when you are pregnant can cause withdrawal symptoms in your newborn baby that may be life-threatening if not recognized and treated.

Use with Benzodiazepines or Other CNS Depressants

Use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, can result in severe drowsiness, breathing problems, coma and death.

IMPORTANT SAFETY INFORMATION

Butrans is a long-acting (extended-release) opioid pain medicine that can put you at risk for overdose and death. Even if you use your dose correctly as prescribed, you are at risk for opioid addiction, abuse and misuse that can lead to death.

Do not use Butrans if you:

  • Have severe asthma, trouble breathing, or other lung problems

  • Have a bowel blockage or narrowing of the stomach or intestines

  • Are allergic to buprenorphine

Before applying Butrans, tell your healthcare provider if you have a history of head injury or seizures; problems breathing or urinating; liver, kidney, thyroid, pancreas, or gallbladder problems; heart rhythm abnormalities (Long QT Syndrome); abuse of street or prescription drugs; alcohol addiction; or mental health problems.

WARNINGS
  • Use of Butrans, even when used as recommended, can result in addiction, abuse and misuse, which could lead to overdose and death.

  • Get emergency help right away if you take too much Butrans (overdose).

  • The risk of serious or life-threatening breathing problems that could lead to death can occur even at recommended doses. The risk is greatest when you first start using Butrans or when your dose is increased. Patients who have lung disease or are elderly, frail, or in poor general health, are at increased risk, especially if Butrans is given with other drugs that cause breathing problems. Seek medical attention immediately if you have trouble breathing.

  • Taking Butrans with other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants (including street drugs) can cause severe drowsiness, decreased awareness, breathing problems, coma, and death. Do not use these together unless you are directed to do so by your healthcare provider.

  • Never give anyone else your Butrans. They could die from using it. Store Butrans away from children and in a safe place to help prevent abuse or theft. Selling or giving away Butrans is against the law.

  • Accidental exposure, especially in a child, may result in breathing problems, overdose, or death. Be sure to store Butrans safely and to dispose of unused patches when Butrans is no longer needed; use the Patch-Disposal Unit or fold the patch in half and flush it down the toilet (see the detailed Instructions for Use provided with the Butrans patch).

  • Tell your healthcare provider if you are pregnant or planning to become pregnant. Prolonged use of Butrans while you are pregnant can cause withdrawal symptoms in your newborn baby that could be life-threatening if not recognized and treated.

  • Tell your healthcare provider if you are breastfeeding. Breastfeeding is not recommended during treatment with Butrans. It may harm your baby.

  • Tell your healthcare provider about any prescription or over-the-counter medicines, vitamins, or herbal supplements you are taking. Using Butrans with certain other medicines can cause serious side effects that could lead to death.

  • When using Butrans, do not drink alcohol or use prescription or over-the-counter medicines containing alcohol. Using products containing alcohol during treatment with Butrans may cause you to overdose and die.

  • Butrans could cause adrenal insufficiency, a potentially life-threatening condition which may cause symptoms of nausea, vomiting, anorexia, fatigue, weakness, dizziness and low blood pressure. Seek medical attention if you experience these symptoms.

  • Butrans may cause symptoms of low blood pressure such as dizziness, lightheadedness, or fainting. If you experience these symptoms, you should sit or lie down and be careful when you get up from a sitting or lying position.

  • Butrans may complicate head injuries. Butrans should not be used by those with disturbances in consciousness or coma.

  • Do not stop using Butrans without talking to your healthcare provider.

  • Tell your healthcare provider if you develop a fever. While using Butrans, do NOT expose Butrans or the skin near where Butrans is applied to hot water or prolonged direct sunlight; avoid sunbathing, taking hot baths, hot tubs, saunas, heating pads, electric blankets, heated waterbeds, and heat or tanning lamps. These activities can increase the amount of medicine your Butrans delivers and cause an overdose that can lead to death.

  • Get emergency medical help if you have trouble breathing, shortness of breath, fast heartbeat, chest pain, swelling of your face, tongue or throat, extreme drowsiness, light-headedness when changing positions feeling faint, agitation, high body temperature, trouble walking, stiff muscles, or mental changes such as confusion.

  • Butrans may increase the frequency of seizures in patients who experience seizures and may increase the risk of seizures in other settings associated with seizures. Tell your healthcare provider if you have a history of seizures.

  • When using Butrans, do not drive or operate heavy machinery until you know how Butrans affects you. Butrans can make you sleepy, dizzy, or lightheaded, and may reduce your mental and physical ability to perform these activities safely.

Side Effects
  • The most common side effects reported by patients treated with Butrans in the clinical trials were nausea, headache, application site itch, dizziness, constipation, sleepiness, vomiting, application site redness, dry mouth, and application site rash. Call your healthcare provider if you have any of these symptoms and they are severe.

  • These are not all the possible side effects of Butrans. Call your doctor for medical advice about side effects.

Please read the Brief Summary and Full Prescribing Information, including Boxed Warning, Medication Guide, and Instructions for Use.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

WARNING: ADDICTION, ABUSE, AND MISUSE; LIFE-THREATENING BREATHING PROBLEMS; ACCIDENTAL EXPOSURE; WITHDRAWAL SYNDROME IN NEWBORNS; and RISKS FROM USE WITH BENZODIAZEPINES OR OTHER CNS DEPRESSANTS

Addiction, Abuse, and Misuse

Butrans is a long-acting (extended-release) opioid pain medicine that can put you and other users at risk for overdose and death. Even if you use your dose correctly as prescribed, you are at risk for opioid addiction, abuse, and misuse that can lead to death.

Life-Threatening Breathing Problems

When you first start using Butrans, or when your dose is increased, serious or life-threatening breathing problems that can lead to death may occur, and may occur even at recommended doses during the normal course of therapy. Do not chew, swallow, snort, or inject buprenorphine from the patch because this can lead to overdose and death.

Accidental Exposure

Accidental exposure, especially in children, may result in breathing problems, overdose, or death.

Withdrawal Syndrome in Newborns

Prolonged use of Butrans when you are pregnant can cause withdrawal symptoms in your newborn baby that may be life-threatening if not recognized and treated.

Use with Benzodiazepines or Other CNS Depressants

Use of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, can result in severe drowsiness, breathing problems, coma and death.

What is Butrans?
  • Butrans is a strong prescription pain medicine that contains an opioid (narcotic). It is used to manage pain severe enough to require daily, around-the-clock, long-term treatment with an opioid, when other pain treatments, such as non-opioid pain medicines (e.g., acetaminophen, ibuprofen, or celecoxib) or immediate-release opioid medicines, do not treat your pain well enough, you experience side effects when taking them, or they are deemed otherwise inadequate.

  • Butrans is only used to treat pain that continues around-the-clock (pain that is constant).

IMPORTANT SAFETY INFORMATION

Butrans is a long-acting (extended-release) opioid pain medicine that can put you at risk for overdose and death. Even if you use your dose correctly as prescribed, you are at risk for opioid addiction, abuse and misuse that can lead to death.

Do not use Butrans if you:

  • Have severe asthma, trouble breathing, or other lung problems

  • Have a bowel blockage or narrowing of the stomach or intestines

  • Are allergic to buprenorphine

Before applying Butrans, tell your healthcare provider if you have a history of head injury or seizures; problems breathing or urinating; liver, kidney, thyroid, pancreas, or gallbladder problems; heart rhythm abnormalities (Long QT Syndrome); abuse of street or prescription drugs; alcohol addiction; or mental health problems.

WARNINGS
  • Use of Butrans, even when used as recommended, can result in addiction, abuse and misuse, which could lead to overdose and death.

  • Get emergency help right away if you take too much Butrans (overdose).

  • The risk of serious or life-threatening breathing problems that could lead to death can occur even at recommended doses. The risk is greatest when you first start using Butrans or when your dose is increased. Patients who have lung disease or are elderly, frail, or in poor general health, are at increased risk, especially if Butrans is given with other drugs that cause breathing problems. Seek medical attention immediately if you have trouble breathing.

  • Taking Butrans with other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants (including street drugs) can cause severe drowsiness, decreased awareness, breathing problems, coma, and death. Do not use these together unless you are directed to do so by your healthcare provider.

  • Never give anyone else your Butrans. They could die from using it. Store Butrans away from children and in a safe place to help prevent abuse or theft. Selling or giving away Butrans is against the law.

  • Accidental exposure, especially in a child, may result in breathing problems, overdose, or death. Be sure to store Butrans safely and to dispose of unused patches when Butrans is no longer needed; use the Patch-Disposal Unit or fold the patch in half and flush it down the toilet (see the detailed Instructions for Use provided with the Butrans patch).

  • Tell your healthcare provider if you are pregnant or planning to become pregnant. Prolonged use of Butrans while you are pregnant can cause withdrawal symptoms in your newborn baby that could be life-threatening if not recognized and treated.

  • Tell your healthcare provider if you are breastfeeding. Breastfeeding is not recommended during treatment with Butrans. It may harm your baby.

  • Tell your healthcare provider about any prescription or over-the-counter medicines, vitamins, or herbal supplements you are taking. Using Butrans with certain other medicines can cause serious side effects that could lead to death.

  • When using Butrans, do not drink alcohol or use prescription or over-the-counter medicines containing alcohol. Using products containing alcohol during treatment with Butrans may cause you to overdose and die.

  • Butrans could cause adrenal insufficiency, a potentially life-threatening condition which may cause symptoms of nausea, vomiting, anorexia, fatigue, weakness, dizziness and low blood pressure. Seek medical attention if you experience these symptoms.

  • Butrans may cause symptoms of low blood pressure such as dizziness, lightheadedness, or fainting. If you experience these symptoms, you should sit or lie down and be careful when you get up from a sitting or lying position.

  • Butrans may complicate head injuries. Butrans should not be used by those with disturbances in consciousness or coma.

  • Do not stop using Butrans without talking to your healthcare provider.

  • Tell your healthcare provider if you develop a fever. While using Butrans, do NOT expose Butrans or the skin near where Butrans is applied to hot water or prolonged direct sunlight; avoid sunbathing, taking hot baths, hot tubs, saunas, heating pads, electric blankets, heated waterbeds, and heat or tanning lamps. These activities can increase the amount of medicine your Butrans delivers and cause an overdose that can lead to death.

  • Get emergency medical help if you have trouble breathing, shortness of breath, fast heartbeat, chest pain, swelling of your face, tongue or throat, extreme drowsiness, light-headedness when changing positions feeling faint, agitation, high body temperature, trouble walking, stiff muscles, or mental changes such as confusion.

  • Butrans may increase the frequency of seizures in patients who experience seizures and may increase the risk of seizures in other settings associated with seizures. Tell your healthcare provider if you have a history of seizures.

  • When using Butrans, do not drive or operate heavy machinery until you know how Butrans affects you. Butrans can make you sleepy, dizzy, or lightheaded, and may reduce your mental and physical ability to perform these activities safely.

Side Effects
  • The most common side effects reported by patients treated with Butrans in the clinical trials were nausea, headache, application site itch, dizziness, constipation, sleepiness, vomiting, application site redness, dry mouth, and application site rash. Call your healthcare provider if you have any of these symptoms and they are severe.

  • These are not all the possible side effects of Butrans. Call your doctor for medical advice about side effects.

Please read the Brief Summary and Full Prescribing Information, including Boxed Warning, Medication Guide, and Instructions for Use.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please read the Brief Summary and Full Prescribing Information, including Boxed Warning, Medication Guide, and Instructions for Use.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.